Vatican Hospital makes important breakthrough in cancer research vaticannews.va

This new discovery opens the way to therapies that block the defense system of diseased cells. After decades of research and many hypotheses, it closes the circle on the mechanisms of the cell cycle, the process through which cells, including cancer cells, mature and proliferate. Researchers at the Bambino Gesù Children’s Hospital and the University of Rome “Tor Vergata”, in collaboration with other European and U.S. research centres, have discovered the missing piece: what regulates the life of Cyclin D, an essential molecule in cell division.

The switch that turns the activity of Cyclin D on and off is a protein called Amber1: when it does not work it triggers a process that leads to the rapid formation of many types of cancer. The discovery opens the way to specific therapies that inhibit the defense system of the diseased cells up to their self-destruction. The results of the study supported by AIRC, have just been published in the scientce magazine Nature…

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